Ozempic After Bariatric Surgery: A Must-Read Guide

Written by Heather Smith, B.S. and medically reviewed by Dr. Stephen Boyce, MD

Key Takeaways

  • Ozempic is a prescription medication that helps people with type 2 diabetes control their blood sugar levels and supports healthy weight management.
  • Ozempic can be a great tool for your health journey if you struggle to manage your blood sugar, if your weight loss has stopped, or if you’ve started to regain weight. 
  • It’s essential to work with your healthcare provider when taking Ozempic to monitor for side effects and prevent any nutritional deficiencies.

Taking Ozempic after bariatric surgery can be a beneficial tool for managing your type 2 diabetes. Combining it with proper bariatric vitamins and supplements can help ensure you maintain optimal health while benefiting from the medication.

While bariatric surgery changes the digestive system to help reduce excess weight, Ozempic reduces appetite and keeps blood sugar in a healthy range. Using these tools together can help you achieve your weight and health goals. Complementing these with bariatric protein shakes or bariatric protein bars can further support muscle retention and nutrition.

However, many people have questions about whether taking Ozempic after bariatric surgery is safe. There are also several factors to consider before adding Ozempic to your health strategies. 

We’ve created this guide to explain everything you need to know about using Ozempic after bariatric surgery. We discuss how it works, when a person may benefit from it, and any risks and considerations.

What is Ozempic, and how does it work?

Ozempic is a prescription medication from the class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists. The main ingredient in Ozempic, semaglutide, mimics a natural hormone in your body that has several functions that affect your appetite and blood sugar levels.

Here is how Ozempic works:

  • Stimulates insulin secretion: When your blood sugar levels are elevated, Ozempic encourages your body to release insulin, helping to lower glucose levels.
  • Reduces glucose production: It inhibits the release of glucagon, a hormone that signals your liver to produce glucose, which can prevent blood sugar spikes.
  • Promotes feeling full: By slowing down how quickly your stomach empties, Ozempic helps you feel fuller longer, reducing appetite and supporting weight loss.

In addition to Ozempic, using bariatric multivitamins or a bariatric multivitamin with iron can prevent nutritional deficiencies common after surgery.

Why might someone need Ozempic after bariatric surgery?

Most people initially lose a significant amount of weight after bariatric surgery. However, for some, this weight loss can slow down, come to a halt, or they may start to regain. 

In these cases, taking Ozempic can help achieve long-term success. However, it’s important to note that Ozempic is only approved by the Food and Drug Association (FDA) for people with type 2 diabetes.

Here are several situations in which Ozempic may be beneficial:

  • Addressing weight regain: Despite initial success, you may regain weight after bariatric surgery due to factors like hormonal changes, lifestyle adjustments, or medical conditions. Ozempic helps promote satiety and enhances the body’s ability to manage blood sugar.
  • Supporting glycemic control: Ozempic helps regulate blood sugar levels by improving insulin sensitivity and reducing glucose production. This is particularly beneficial if you have type 2 diabetes and your blood sugar levels remain elevated despite surgery.
  • Adjunct to lifestyle changes: While surgery lays the foundation for weight loss, maintaining those results often requires ongoing lifestyle modifications, such as healthy eating and regular exercise. Ozempic complements these efforts by making it easier to manage hunger and maintain a lower calorie intake.
  • Preventing long-term complications: Ozempic helps reduce the risk of cardiovascular events such as heart attacks and stroke in people with type 2 diabetes. 

When is it appropriate to start Ozempic after bariatric surgery?

The best time to start taking Ozempic after bariatric surgery varies from person to person. It depends on several factors, such as individual recovery, health goals, and medical needs. 

After having bariatric surgery, giving your body time to heal and adjust before introducing Ozempic is essential.

Many health professionals recommend waiting at least six months to two years after surgery before starting a medication like Ozempic.

Ultimately, you should make the decision to take Ozempic with your healthcare provider. They can help you decide if and when the medication will benefit your situation and provide the necessary monitoring.

Are there any risks or contraindications of using Ozempic after bariatric surgery?

Like all medications, there are several side effects and potential risks to consider. Understanding these can help you make your decision, and you’ll also know what to monitor for. 

Potential Risks:

  • Gastrointestinal issues: The most common side effects include nausea, vomiting, diarrhea, and constipation. 
  • Risk of hypoglycemia: Taking ozempic along with other diabetes medications, such as insulin or metformin, puts you at a higher risk of developing low blood sugar, also called hypoglycemia. 
  • Nutritional deficiencies: Bariatric surgery increases the risk of nutritional deficiencies, and taking Ozempic, which reduces appetite, can further increase the risk.

Contraindications:

The manufacturer of Ozempic warns that certain people should not take this medication. 

If you have a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN2), you should avoid taking Ozempic.

If you’ve ever had problems with your gallbladder or pancreas, you’ll want to discuss the risks of taking Ozempic with your health professional. 

Lastly, if you are allergic to any of the ingredients in Ozempic, you should avoid taking this medication. 

Can Ozempic interfere with the benefits of bariatric surgery?

Ozempic does not directly interfere with the benefits of bariatric surgery. Alternatively, it helps support the benefits of the surgery.

Ozempic slows the rate at which food leaves your stomach, helping to curb your appetite and lower your calorie intake. This action further supports healthy weight management.

Bariatric surgery and Ozempic also support healthy blood sugar levels. Surgery often reduces insulin resistance, while Ozempic stimulates insulin secretion and lowers glucose production. 

However, a potential challenge is nutritional deficiencies. 

Bariatric surgery reduces how much nutrition your body absorbs, while Ozempic reduces feelings of hunger. It’s very important that you work with a registered dietitian to ensure you are getting all the essential vitamins, minerals, and nutrients your body needs for optimal health. 

How effective is Ozempic in managing weight regain after bariatric surgery?

While no specific studies have examined how Ozempic affects weight loss after bariatric surgery, several studies have examined how semaglutide, the main ingredient in Ozempic, affects weight loss after bariatric surgery. 

These studies suggest that taking semaglutide after bariatric surgery helps people lose an additional 10-15% of their body weight when combined with a healthy diet and regular exercise. This aligns with strategies that may involve using other weight loss medications after bariatric surgery to maintain results.

However, it’s important to keep in mind that individual results vary and depend on several factors, such as following a healthy diet and exercising regularly.  

What should I discuss with my doctor before starting Ozempic?

Before taking Ozempic, it’s important to talk with your healthcare provider to ensure that it is a safe and beneficial medication for you. 

Here are several key topics to discuss with them:

  • Risks: Discuss the risk factors of taking Ozempic and whether your personal or family medical history puts you at higher risk for complications. 
  • Benefits: Explore the possible benefits taking Ozempic could have on your overall health and in reaching your health goals. 
  • Nutrition status: Talk with your healthcare provider or a registered dietitian about a healthy eating plan to keep you on track with meeting your nutritional needs. 
  • Monitoring: Talk with your healthcare provider about how they will monitor your overall health if you start taking Ozempic.
  • Medications: Ensure your healthcare provider is aware of your current medications and supplements to ensure no contraindications between them and Ozempic.
  • Lifestyle changes: Ask about how to combine Ozempic with diet, exercise, and other lifestyle changes to gain the best results.

Conclusion

Ozempic can be a valuable tool for managing blood sugar levels, weight regain, or a stall in weight loss after bariatric surgery. However, you must carefully consider the benefits and risks with your healthcare provider.

It is best to give your body time to heal after bariatric surgery before starting Ozempic. Health professionals suggest waiting six months to two years after surgery.

When taken with your healthcare provider and a registered dietitian’s guidance, Ozempic can profoundly benefit your overall health and help you meet your health goals.  

If you want to learn more, why not check out these articles below: 

References

Anderson, L., (2024). What is Ozempic used for and how does it work? Drugs.com.

Ozempic. (N.D.) Novo Nordisk.

Pratama, K., et al. (2024). Glucagon-like peptide-1 receptor agonists for post-bariatric surgery weight regain and insufficient weight loss: A systematic review. Obesity Medicine.

Le, R., (2024). Cardiovascular Protective Properties of GLP-1 Receptor Agonists: More than Just Diabetic and Weight Loss Drugs. J. Clin. Med.

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